Mounjaro (Zepbound)
What Is Mounjaro (Zepbound)?
Mounjaro (aka tirzepatide) is the newest injectable medication for the treatment of type II diabetes and obesity (under the brand name Zepbound). Based on the results of the SURMOUNT trial, Mounjaro (Zepbound) is the most effective obesity medication ever.
Who Is Mounjaro (Zepbound) For?
Mounjaro is intended for adults with a body mass index greater than 30, or greater than 27 with an obesity-related medical condition (i.e. diabetes, high blood pressure, high cholesterol, sleep apnea). Candidates must be willing and comfortable to use a weekly, injectable medication, and—this is critically important—willing to use the medication on a long-term basis. Obesity is a chronic and relapsing condition, therefore medications like Mounjaro are not designed for short-term use.
*Mounjaro (tirzepatide) is currently FDA approved for the treatment of type 2 diabetes in adults, while Zepbound is FDA approved for the treatment of obesity.
Cuánto peso perderá
The recently published SURMOUNT trial established the efficacy of Mounjaro/Zepbound. In this phase 3, controlled study, 2,539 people were randomized to receive either tirzepatide (at 5, 10 or 15 mg) or a placebo. After 72 weeks of treatment, the following results were observed:
- With the placebo, the average weight loss was 3.1 percent.
- With 5 mg tirzepatide, the average weight loss was 15 percent.
- With 10 mg tirzepatide, weight loss increased to 19 percent.
- At 15 mg, the average weight loss was a remarkable 20.9 percent.
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What is Mounjaro? How does it work?
How is Mounjaro administered?
Mounjaro comes in single-use, pre-filled pens. Each pen is 1 dose. To use the pen, simply remove the cap, turn to unlock the pen, and press the pen firmly against the skin. Press the pen button until a click is heard. The medication will be delivered subcutaneously. A second click will be heard when the medication is fully delivered. Most patients inject the medication in the upper arm, belly, or thigh.
How often do I take the medication?
How is the does adjusted over time?
The starting dose is 2.5 mg, which is taken once weekly for a month. The dose can then be increased to 5 mg, also taken for a month. The dose can be further increased by 2.5 mg every month, up to a maximum dose of 15 mg. This process can take up to 20 weeks.
How long do I stay on the medication?
Mounjaro is considered a long-term medication. If you are tolerating it well, and it is helping you to lose weight, it is recommended to continue the medication.
What are the most common side effects?
How do I know if I am a candidate for Mounjaro drug therapy?
I have a thyroid disorder, can I use Mounjaro?
Mounjaro is contraindicated in patients with a personal or family history of medullary thyroid cancer, which is a rare type of thyroid cancer. However, it is safe to use if you have a history of hypothyroidism, or hyperthyroidism, or currently take thyroid medication.
